The Milan to Lake Como train time takes 40 minutes to 1 hour. The Cost is only $5 for the train. Once you reach your chosen station, it’s easy to hop onto a ferry see the timetables at Navigazione Laghi or slow boat that will take you across the lake. You can expect the journey from Lucerne to Como by train to take around 4 hours 7 minutes. If you want to get there as quickly as possible, it can take as little as 3 hours 17 minutes on the fastest services. You'll usually find around 28 trains per day running on this route, which spans 150 km. You'll have to make 1 change along the way on Save. High speed train from Rome to Milan is about 3 hours. From Lake Como to Milan is about 1.5 hours from either Varenna or Como. With the high speed train (Frece Rosa) you can easily do the trip in about a little more than half a day if you time your transfers well. You should go to Varenna. From Milan Central, you'll want to catch a train to Como S. Giovanni. I'm not sure you'll make the last C10 bus to Tremezzo, which is at 8.24 p.m., but it's usually easy to grab a cab out front of the station in any case. 2. Swiss Railways (SBB/CFF/FFS) operates a train from Como S.Giovanni to Milano Centrale hourly. Tickets cost €22 - €40 and the journey takes 41 min. Two other operators also service this route. Alternatively, FlixBus operates a bus from Como to Milan 3 times a day. Como -> Milan (approx 6pm) We caught the train back to Milan as the sun was setting. As it was only March it started to get cooler, and all in all it had been a long day. We arrived back at Milan Central Station in time to rest & freshen up before heading into the city for evening drinks. Single ticket: €4.80. The most straightforward way is probably looking at Mennagio -> ferry to Varrena -> train to Milan -> train to Milan Malpensa which is never going to be fast. The Varenna to MXP section is about 2:15 at the best of times. The ferry to Como from Mennagio is >2 hours all by itself so again not fast. Como to Dolomites Railway by train, bus and walk. The journey time between Como and Dolomites Railway is around 6h 51m and covers a distance of around 463 km. This includes an average layover time of around 1h 26m. Operated by Swiss Railways (SBB/CFF/FFS), Trenitalia EuroCity, Trenitalia Frecce and others, the Como to Dolomites Railway service cAGdg.